Affecting a global population of four million individuals, Crohn’s disease emerges as a significant health concern. This ailment induces incapacitating symptoms including persistent fatigue, diarrhea, abdominal distress, weight reduction, and malnutrition. Once symptomatic, Crohn’s becomes a lifelong companion, with symptom management being the sole recourse during flare-ups due to the absence of a definitive cure.

The precise etiology of Crohn’s disease remains elusive, likely arising from an intricate interplay of various factors such as genetics, environmental triggers (including smoking), and an overly reactive immune system within the gastrointestinal tract. Research has also illuminated the vital role played by the gut microbiome in this condition.

Comprising an assortment of trillions of bacteria, viruses, and fungi, the gut microbiome establishes its presence from birth and undertakes the pivotal task of sustaining the proper functioning of intestinal cells and the entire digestive system. Moreover, the bacterial inhabitants of the gut significantly contribute to the optimal performance of immune cells, ensuring their effectiveness.

Numerous studies underscore that individuals afflicted with Crohn’s disease exhibit a less diverse array of gut bacteria. Additionally, they manifest heightened levels of specific bacterial strains capable of inciting inflammation within the gastrointestinal tract.